About 5 results found for searched term "SD-36" (0.191 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21159 | SD-36 | PROTAC |
| SD-36 is a potent STAT3 PROTAC degradation agent (Kd=~50 nM) with a high selectivity compared to other STAT members. SD-36 is composed of the STAT3 inhibitor SI-109, a linker, and an analog of Cereblon ligand Lenalidomide for E3 ubiquitin ligase. | ||
| M2897 | OG-L002 | Histone demethylase |
| OG-L002 is a potent and specific LSD1 inhibitor with IC50 of 20 nM, exhibiting 36- and 69-fold selectivity over MAO-B and MAO-A, respectively. | ||
| M21406 | SI-109 | STAT |
| SI-109 is a potent STAT3 SH2 domain structural domain inhibitor (Ki=9 nM) with antitumor activity. si-109 effectively inhibits the transcriptional activity of STAT3 (IC50=3 μM). si-109 and the CRBN analogue lenalidomide ligand were used to design the PROTAC STAT3 degradation agent SD- 36. | ||
| M25458 | UNC8153 | Others |
| UNC-8153 | ||
| UNC8153 is a novel NSD2-targeted degrader that potently and selectively reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. | ||
| M54400 | HAEGTFTSD | Glucagon Receptor |
| HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
